The positive prognostic effect of stromal CD8+ tumor-infiltrating T cells is restrained by the expression of HLA-E in non-small cell lung carcinoma

INTRODUCTION: Tumor-infiltrating CD8+ T cells are associated with improved clinical outcomes in non-small cell lung cancer (NSCLC). Here we studied their prognostic effect in the context of the expression of HLA molecules that are key in tumor recognition (HLA-A, B and C) or suppression of immunity...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Yazdi, Mehrdad Talebian, van Riet, Sander, van Schadewijk, Annemarie, Fiocco, Marta, van Hall, Thorbald, Taube, Christian, Hiemstra, Pieter S., van der burg, Sjoerd H.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823121/
https://ncbi.nlm.nih.gov/pubmed/26658106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6506
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