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Infiltrating CTLs are bothered by HLA-E on tumors
We recently described the upregulation of HLA-E in ovarian and cervical cancers. Instead of interacting with natural killer cells, HLA-E appeared to inhibit intratumoral cytotoxic T lymphocytes (CTL) via the receptor CD94/NKG2A. Strikingly, the survival benefit of intraepithelial infiltrating CTL wa...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376958/ https://ncbi.nlm.nih.gov/pubmed/22720221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.1.17961 |
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