HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8(+) T lymphocytes

HLA-E is a nonclassical HLA class I molecule, which differs from classical HLA molecules by its nonpolymorphic, conserved nature. Expression and function of HLA-E in normal tissues and solid tumors is not fully understood. We investigated HLA-E protein expression on tissue sections of 420 ovarian an...

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Detalhes bibliográficos
Main Authors: Gooden, Marloes, Lampen, Margit, Jordanova, Ekaterina S., Leffers, Ninke, Trimbos, J. Baptist, van der Burg, Sjoerd H., Nijman, Hans, van Hall, Thorbald
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127933/
https://ncbi.nlm.nih.gov/pubmed/21670276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100354108
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