Deficiency of endogenous acute phase serum amyloid A protects apoE−/− mice from angiotensin II-induced abdominal aortic aneurysm formation

OBJECTIVE: Rupture of abdominal aortic aneurysm (AAA), a major cause of death in the aged population, is characterized by vascular inflammation and matrix degradation. Serum amyloid A (SAA), an acute phase reactant linked to inflammation and matrix metalloproteinase induction, correlates with aortic...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Webb, NR, De Beer, MC, Wroblewski, JM, Ji, A, Bailey, W, Shridas, P, Charnigo, RJ, Noffsinger, VP, Witta, J, Howatt, DA, Balakrishnan, A, Rateri, DL, Daugherty, A, De Beer, FC
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823018/
https://ncbi.nlm.nih.gov/pubmed/25745063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304776
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