Immune Checkpoint Blockade to Improve Tumor Infiltrating Lymphocytes for Adoptive Cell Therapy

Tumor-infiltrating lymphocytes (TIL) has been associated with improved survival in cancer patients. Within the tumor microenvironment, regulatory cells and expression of co-inhibitory immune checkpoint molecules can lead to the inactivation of TIL. Hence, there is a need to develop strategies that d...

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Опубликовано в: :PLoS One
Главные авторы: Kodumudi, Krithika N., Siegel, Jessica, Weber, Amy M., Scott, Ellen, Sarnaik, Amod A., Pilon-Thomas, Shari
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822778/
https://ncbi.nlm.nih.gov/pubmed/27050669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153053
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