T cell mediated immunity after combination therapy with intralesional PV-10 and blockade of the PD-1/PD-L1 pathway in a murine melanoma model

Intralesional (IL) injection of Rose Bengal (PV-10) induces regression of injected and uninjected lesions in several murine tumor models. In this study, we investigated the anti-tumor response of combining IL PV-10 with blockade of the PD-1 / PD-L1 pathway and the role of immune cell populations in...

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Vydáno v:PLoS One
Hlavní autoři: Liu, Hao, Weber, Amy, Morse, Jennifer, Kodumudi, Krithika, Scott, Ellen, Mullinax, John, Sarnaik, Amod A., Pilon-Thomas, Shari
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918896/
https://ncbi.nlm.nih.gov/pubmed/29694419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196033
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