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Blockade of myeloid derived suppressor cells after induction of lymphopenia improves adoptive T cell therapy in a murine model of melanoma
Administration of non-myeloablative chemotherapeutic agents or total body irradiation (TBI) prior to adoptive transfer of tumor-specific T cells may reduce or eliminate immunosuppressive populations such as T regulatory cells (Tregs) and myeloid derived suppressor cells (MDSC). Little is known about...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505990/ https://ncbi.nlm.nih.gov/pubmed/23100512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200274 |
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