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Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses

Oncolytic viruses (OVs) are unique anticancer agents based on their pleotropic modes of action, which include, besides viral tumor cell lysis, activation of antitumor immunity. A panel of diverse viruses, often genetically engineered, has advanced to clinical investigation, including phase 3 studies...

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書目詳細資料
發表在:Mol Ther Methods Clin Dev
Main Authors: Ungerechts, Guy, Bossow, Sascha, Leuchs, Barbara, Holm, Per S, Rommelaere, Jean, Coffey, Matt, Coffin, Rob, Bell, John, Nettelbeck, Dirk M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822647/
https://ncbi.nlm.nih.gov/pubmed/27088104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.18
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