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Spironolactone blocks Epstein–Barr virus production by inhibiting EBV SM protein function

Clinically available drugs active against Epstein–Barr virus (EBV) and other human herpesviruses are limited to those targeting viral DNA replication. To identify compounds directed against other steps in the viral life cycle, we searched for drugs active against the EBV SM protein, which is essenti...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Verma, Dinesh, Thompson, Jacob, Swaminathan, Sankar
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822607/
https://ncbi.nlm.nih.gov/pubmed/26976570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523686113
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