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Spironolactone blocks Epstein–Barr virus production by inhibiting EBV SM protein function

Clinically available drugs active against Epstein–Barr virus (EBV) and other human herpesviruses are limited to those targeting viral DNA replication. To identify compounds directed against other steps in the viral life cycle, we searched for drugs active against the EBV SM protein, which is essenti...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Verma, Dinesh, Thompson, Jacob, Swaminathan, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822607/
https://ncbi.nlm.nih.gov/pubmed/26976570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523686113
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