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A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor
Neurofibromatosis type 1 (NF1) is a common genetic disorder that predisposes affected individuals to tumours. The NF1 gene encodes a RAS GTPase-activating protein called neurofibromin and is one of several genes that (when mutant) affect RAS–MAPK signalling, causing related diseases collectively kno...
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| Publicado no: | Nat Rev Cancer |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4822336/ https://ncbi.nlm.nih.gov/pubmed/25877329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3911 |
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