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A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor

Neurofibromatosis type 1 (NF1) is a common genetic disorder that predisposes affected individuals to tumours. The NF1 gene encodes a RAS GTPase-activating protein called neurofibromin and is one of several genes that (when mutant) affect RAS–MAPK signalling, causing related diseases collectively kno...

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Detaylı Bibliyografya
Yayımlandı:Nat Rev Cancer
Asıl Yazarlar: Ratner, Nancy, Miller, Shyra J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822336/
https://ncbi.nlm.nih.gov/pubmed/25877329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3911
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