Safety and tolerability of BAN2401 - a clinical study in Alzheimer’s disease with a protofibril selective Aβ antibody

BACKGROUND: Several monoclonal antibodies for the treatment of Alzheimer’s disease (AD) have been in development over the last decade. BAN2401 is a monoclonal antibody that selectively binds soluble amyloid β (Aβ) protofibrils. METHODS: Here we describe the first clinical study with BAN2401. Safety...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Logovinsky, Veronika, Satlin, Andrew, Lai, Robert, Swanson, Chad, Kaplow, June, Osswald, Gunilla, Basun, Hans, Lannfelt, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822297/
https://ncbi.nlm.nih.gov/pubmed/27048170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-016-0181-2
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