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Targeted resequencing and variant validation using pxlence PCR assays

The advent of next-generation sequencing technologies had a profound impact on molecular diagnostics. PCR is a popular method for target enrichment of disease gene panels. Using our proprietary primer-design pipeline, primerXL, we have created almost one million assays covering over 98% of the human...

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Detalhes bibliográficos
Publicado no:Biomol Detect Quantif
Main Authors: Coppieters, Frauke, Verniers, Kimberly, De Leeneer, Kim, Vandesompele, Jo, Lefever, Steve
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822215/
https://ncbi.nlm.nih.gov/pubmed/27077044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bdq.2015.09.001
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