Creating a Prosurvival Phenotype through a Histone Deacetylase Inhibitor in a Lethal Two-Hit Model

OBJECTIVES: Hemorrhagic shock (HS) can initiate an exaggerated systemic inflammatory response and multiple organ failure, especially if followed by a subsequent inflammatory insult (“second hit”). We have recently shown that histone deacetylase inhibitors can improve survival in rodent models of HS...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Liu, Zhengcai, Li, Yongqing, Chong, Wei, Deperalta, Danielle K., Duan, Xiuzhen, Liu, Baoling, Halaweish, Ihab, Zhou, Peter, Alam, Hasan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822203/
https://ncbi.nlm.nih.gov/pubmed/24430491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000074
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