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Engineered kinesin motor proteins amenable to small-molecule inhibition
The human genome encodes 45 kinesin motor proteins that drive cell division, cell motility, intracellular trafficking and ciliary function. Determining the cellular function of each kinesin would benefit from specific small-molecule inhibitors. However, screens have yielded only a few specific inhib...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4822052/ https://ncbi.nlm.nih.gov/pubmed/27045608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11159 |
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