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A general strategy for expanding polymerase function by droplet microfluidics

Polymerases that synthesize artificial genetic polymers hold great promise for advancing future applications in synthetic biology. However, engineering natural polymerases to replicate unnatural genetic polymers is a challenging problem. Here we present droplet-based optical polymerase sorting (DrOP...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Larsen, Andrew C., Dunn, Matthew R., Hatch, Andrew, Sau, Sujay P., Youngbull, Cody, Chaput, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822039/
https://ncbi.nlm.nih.gov/pubmed/27044725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11235
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