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A general strategy for expanding polymerase function by droplet microfluidics

Polymerases that synthesize artificial genetic polymers hold great promise for advancing future applications in synthetic biology. However, engineering natural polymerases to replicate unnatural genetic polymers is a challenging problem. Here we present droplet-based optical polymerase sorting (DrOP...

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發表在:Nat Commun
Main Authors: Larsen, Andrew C., Dunn, Matthew R., Hatch, Andrew, Sau, Sujay P., Youngbull, Cody, Chaput, John C.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822039/
https://ncbi.nlm.nih.gov/pubmed/27044725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11235
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