Dopaminergic Neurons Exhibit an Age-Dependent Decline in Electrophysiological Parameters in the MitoPark Mouse Model of Parkinson's Disease

Dopaminergic neurons of the substantia nigra (SN) play a vital role in everyday tasks, such as reward-related behavior and voluntary movement, and excessive loss of these neurons is a primary hallmark of Parkinson's disease (PD). Mitochondrial dysfunction has long been implicated in PD and many...

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Foilsithe in:J Neurosci
Main Authors: Branch, Sarah Y., Chen, Cang, Sharma, Ramaswamy, Lechleiter, James D., Li, Senlin, Beckstead, Michael J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2016
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821912/
https://ncbi.nlm.nih.gov/pubmed/27053209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1395-15.2016
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