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Rationally reduced libraries for combinatorial pathway optimization minimizing experimental effort
Rational flux design in metabolic engineering approaches remains difficult since important pathway information is frequently not available. Therefore empirical methods are applied that randomly change absolute and relative pathway enzyme levels and subsequently screen for variants with improved perf...
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| Gepubliceerd in: | Nat Commun |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821882/ https://ncbi.nlm.nih.gov/pubmed/27029461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11163 |
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