Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability

Temporal regulation of microtubule dynamics is essential for proper progression of mitosis and control of microtubule plus-end tracking proteins by phosphorylation is an essential component of this regulation. Here we show that Aurora B and CDK1 phosphorylate microtubule end-binding protein 2 (EB2)...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Iimori, Makoto, Watanabe, Sugiko, Kiyonari, Shinichi, Matsuoka, Kazuaki, Sakasai, Ryo, Saeki, Hiroshi, Oki, Eiji, Kitao, Hiroyuki, Maehara, Yoshihiko
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821873/
https://ncbi.nlm.nih.gov/pubmed/27030108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11117
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