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How drug resistance takes shape

Mutations in a hormone receptor can lead to therapeutic resistance by making it less able to bind and respond to hormone blocking drugs and by making it active, even when the hormome is not present.

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Jeselsohn, Rinath, Brown, Myles
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821798/
https://ncbi.nlm.nih.gov/pubmed/27010172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14973
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