Effects of Antenatal Lipopolysaccharide and Postnatal Hyperoxia on Airway Reactivity and Remodeling in a Neonatal Mouse Model

BACKGROUND: Antenatal inflammation and preterm birth are associated with the development of airway diseases such as wheezing and asthma. Utilizing a newborn mouse model, we assessed the effects of maternal inflammation and postnatal hyperoxia on the neonatal airway. METHODS: Pregnant C57/Bl6 dams we...

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Bibliographic Details
Published in:Pediatr Res
Main Authors: Faksh, Arij, Britt, Rodney D., Vogel, Elizabeth R., Kuipers, Ine, Thompson, Michael A., Sieck, Gary C., Pabelick, Christina M., Martin, Richard J., Prakash, YS
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821779/
https://ncbi.nlm.nih.gov/pubmed/26539665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2015.232
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