Moderate Hyperoxia Induces Extracellular Matrix Remodeling by Human Fetal Airway Smooth Muscle Cells

BACKGROUND: Premature infants are at increased risk for airway diseases, such as wheezing and asthma, because of early exposure to risk factors including hyperoxia. As in adult asthma, airway remodeling and increased extracellular matrix (ECM) deposition is involved. METHODS: We assessed the impact...

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Bibliographic Details
Published in:Pediatr Res
Main Authors: Vogel, Elizabeth R., Britt, Rodney D., Faksh, Arij, Kuipers, Ine, Pandya, Hitesh, Prakash, YS, Martin, Richard J., Pabelick, Christina M.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309184/
https://ncbi.nlm.nih.gov/pubmed/27925619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.218
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