Soluble guanylate cyclase modulators blunt hyperoxia effects on calcium responses of developing human airway smooth muscle

Exposure to moderate hyperoxia in prematurity contributes to subsequent airway dysfunction and increases the risk of developing recurrent wheeze and asthma. The nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic GMP (cGMP) axis modulates airway tone by regulating airway smooth muscle (ASM) int...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Britt, Rodney D., Thompson, Michael A., Kuipers, Ine, Stewart, Alecia, Vogel, Elizabeth R., Thu, James, Martin, Richard J., Pabelick, Christina M., Prakash, Y. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Rapid Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572415/
https://ncbi.nlm.nih.gov/pubmed/26254425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00232.2015
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