IN UTERO NICOTINE EXPOSURE EPIGENETICALLY ALTERS FETAL CHROMATIN STRUCTURE AND DIFFERENTIALLY REGULATES TRANSCRIPTION OF THE GLUCOCORTICOID RECEPTOR IN A RAT MODEL

BACKGROUND: Fetal exposure to nicotine is not limited to maternal tobacco smoke, as electronic cigarettes have an increased prevalence of use among reproductive aged women. Animal models have shown that nicotine exposure in utero is associated with increased risk of asthma and cognitive deficits, as...

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Publicado en:Birth Defects Res A Clin Mol Teratol
Autores principales: Suter, Melissa A., Abramovici, Adi R., Griffin, Ms. Emily, Branch, D. Ware, Lane, Robert H., Mastrobattista, Joan, Rehan, Virender, Aagaard, Kjersti
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821574/
https://ncbi.nlm.nih.gov/pubmed/26172404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23395
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