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IN UTERO NICOTINE EXPOSURE EPIGENETICALLY ALTERS FETAL CHROMATIN STRUCTURE AND DIFFERENTIALLY REGULATES TRANSCRIPTION OF THE GLUCOCORTICOID RECEPTOR IN A RAT MODEL

BACKGROUND: Fetal exposure to nicotine is not limited to maternal tobacco smoke, as electronic cigarettes have an increased prevalence of use among reproductive aged women. Animal models have shown that nicotine exposure in utero is associated with increased risk of asthma and cognitive deficits, as...

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Detalhes bibliográficos
Publicado no:Birth Defects Res A Clin Mol Teratol
Main Authors: Suter, Melissa A., Abramovici, Adi R., Griffin, Ms. Emily, Branch, D. Ware, Lane, Robert H., Mastrobattista, Joan, Rehan, Virender, Aagaard, Kjersti
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821574/
https://ncbi.nlm.nih.gov/pubmed/26172404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23395
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