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IN UTERO TOBACCO EXPOSURE EPIGENETICALLY MODIFIES PLACENTAL CYP1A1 EXPRESSION

The metabolic pathways utilized by higher eukaryotic organisms to deal with potentially carcinogenic xenobiotic compounds from tobacco smoke have been well characterized. Carcinogenic compounds such as polycyclic aromatic hydrocarbons are metabolized sequentially in two-phases: in phase I CYP1A1 cat...

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Detalhes bibliográficos
Main Authors: Suter, Melissa, Abramovici, Adi, Showalter, Lori, Hu, Min, Shope, Cynthia Do, Varner, Michael, Aagaard-Tillery, Kjersti
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921565/
https://ncbi.nlm.nih.gov/pubmed/20462615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2010.01.013
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