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IN UTERO TOBACCO EXPOSURE EPIGENETICALLY MODIFIES PLACENTAL CYP1A1 EXPRESSION

The metabolic pathways utilized by higher eukaryotic organisms to deal with potentially carcinogenic xenobiotic compounds from tobacco smoke have been well characterized. Carcinogenic compounds such as polycyclic aromatic hydrocarbons are metabolized sequentially in two-phases: in phase I CYP1A1 cat...

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Bibliografische gegevens
Hoofdauteurs: Suter, Melissa, Abramovici, Adi, Showalter, Lori, Hu, Min, Shope, Cynthia Do, Varner, Michael, Aagaard-Tillery, Kjersti
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921565/
https://ncbi.nlm.nih.gov/pubmed/20462615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2010.01.013
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