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IN UTERO TOBACCO EXPOSURE EPIGENETICALLY MODIFIES PLACENTAL CYP1A1 EXPRESSION

The metabolic pathways utilized by higher eukaryotic organisms to deal with potentially carcinogenic xenobiotic compounds from tobacco smoke have been well characterized. Carcinogenic compounds such as polycyclic aromatic hydrocarbons are metabolized sequentially in two-phases: in phase I CYP1A1 cat...

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Detaylı Bibliyografya
Asıl Yazarlar: Suter, Melissa, Abramovici, Adi, Showalter, Lori, Hu, Min, Shope, Cynthia Do, Varner, Michael, Aagaard-Tillery, Kjersti
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921565/
https://ncbi.nlm.nih.gov/pubmed/20462615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2010.01.013
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