IN UTERO TOBACCO EXPOSURE EPIGENETICALLY MODIFIES PLACENTAL CYP1A1 EXPRESSION

The metabolic pathways utilized by higher eukaryotic organisms to deal with potentially carcinogenic xenobiotic compounds from tobacco smoke have been well characterized. Carcinogenic compounds such as polycyclic aromatic hydrocarbons are metabolized sequentially in two-phases: in phase I CYP1A1 cat...

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Hlavní autoři: Suter, Melissa, Abramovici, Adi, Showalter, Lori, Hu, Min, Shope, Cynthia Do, Varner, Michael, Aagaard-Tillery, Kjersti
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921565/
https://ncbi.nlm.nih.gov/pubmed/20462615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2010.01.013
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