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Mutational probing of protein aggregates to design aggregation‐resistant proteins

Characterization of amorphous protein aggregates may offer insights into the process of aggregation. Eleven single amino acid mutants of lipase (LipA of Bacillus subtilis) were subjected to temperature‐induced aggregation, and the resultant aggregates were characterized for recovery of activity in t...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Kamal, Mohamad Zahid, Kumar, Virender, Satyamurthi, Kundarapu, Das, Kushal Kumar, Rao, Nalam Madhusudhana
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821347/
https://ncbi.nlm.nih.gov/pubmed/27239434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12003
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