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Beyond the glutamine expansion: Influence of post-translational modifications of Ataxin-1 in the pathogenesis of spinocerebellar ataxia type 1

Post-translational modifications are crucial mechanisms that modulate various cellular signaling pathways, and their dysregulation is associated with many human diseases. Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease characterized by progressive ataxia, mil...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Ju, Hyoungseok, Kokubu, Hiroshi, Lim, Janghoo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821199/
https://ncbi.nlm.nih.gov/pubmed/24752589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8703-z
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