Polyglutamine Disease Toxicity Is Regulated by Nemo-like Kinase in Spinocerebellar Ataxia Type 1

Polyglutamine diseases are dominantly inherited neurodegenerative diseases caused by an expansion of a CAG trinucleotide repeat encoding a glutamine tract in the respective disease-causing proteins. Extensive studies have been performed to unravel disease pathogenesis and to develop therapeutics. He...

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Main Authors: Ju, Hyoungseok, Kokubu, Hiroshi, Todd, Tiffany W., Kahle, Juliette J., Kim, Soeun, Richman, Ronald, Chirala, Karthik, Orr, Harry T., Zoghbi, Huda Y., Lim, Janghoo
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2013
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710458/
https://ncbi.nlm.nih.gov/pubmed/23719801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3465-12.2013
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