The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells

Estrogen is synthesized from cholesterol and high cholesterol levels are suggested to be associated with increased risk of estrogen receptor(ER)-positive breast cancer. The cholesterol metabolite 27-hydroxycholesterol (27-OHC) was recently identified as a selective estrogen receptor modulator (SERM)...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cell Biochem
Main Authors: Raza, Shaneabbas, Ohm, Joyce E., Dhasarathy, Archana, Schommer, Jared, Roche, Conor, Hammer, Kimberly D. P., Ghribi, Othman
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821067/
https://ncbi.nlm.nih.gov/pubmed/26350565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-015-2551-7
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker