Functional Importance of Regional Differences in Localized Gene Expression of Receptors for IL-13 in Murine Gut

IL-13 induces a STAT6-dependent hypercontractility of intestinal smooth muscle that is mediated by binding to the IL-13Rα1 component of the type 2 IL-4R that is linked to STAT6. IL-13 also binds to the IL-13Rα2 that is not linked to STAT6 and functions to limit the effects of IL-13 in vivo. In this...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Morimoto, Motoko, Morimoto, Masahiro, Zhao, Aiping, Madden, Kathleen B., Dawson, Harry, Finkelman, Fred D., Mentink-Kane, Margaret, Urban, Joseph F., Wynn, Thomas A., Shea-Donohue, Terez
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821014/
https://ncbi.nlm.nih.gov/pubmed/16365442
Tagiau: Ychwanegu Tag
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