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Functional Importance of Regional Differences in Localized Gene Expression of Receptors for IL-13 in Murine Gut
IL-13 induces a STAT6-dependent hypercontractility of intestinal smooth muscle that is mediated by binding to the IL-13Rα1 component of the type 2 IL-4R that is linked to STAT6. IL-13 also binds to the IL-13Rα2 that is not linked to STAT6 and functions to limit the effects of IL-13 in vivo. In this...
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| Publicat a: | J Immunol |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821014/ https://ncbi.nlm.nih.gov/pubmed/16365442 |
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