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Interleukin-13 Receptor α1-Dependent Responses in the Intestine Are Critical to Parasite Clearance
Nematode infection upregulates interleukin-4 (IL-4) and IL-13 and induces STAT6-dependent changes in gut function that promote worm clearance. IL-4 and IL-13 activate the type 2 IL-4 receptor (IL-4R), which contains the IL-13Rα1 and IL-4Rα chains. We used mice deficient in IL-13Rα1 (IL-13Rα1(−/−)) t...
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| Publicado no: | Infect Immun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807467/ https://ncbi.nlm.nih.gov/pubmed/26810038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00990-15 |
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