Critical Role of IL-25 in Nematode Infection-Induced Alterations in Intestinal Function

IL-25 (IL-17E) is a member of IL-17 cytokine family. IL-25-deficient mice exhibit impaired Th2 immunity against nematode infection, implicating IL-25 as a key component in mucosal immunity. The sources of IL-25 and mechanisms responsible for the induction of Th2 immunity by IL-25 in the gastrointest...

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Main Authors: Zhao, Aiping, Urban, Joseph F., Sun, Rex, Stiltz, Jennifer, Morimoto, Motoko, Notari, Luigi, Madden, Kathleen B., Yang, Zhonghan, Grinchuk, Viktoriya, Ramalingam, Thirumalai R., Wynn, Thomas A., Shea-Donohue, Terez
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988083/
https://ncbi.nlm.nih.gov/pubmed/20974983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000450
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