Interleukin-25 or IL-17E protects against high-fat diet-induced hepatic steatosis in mice dependent upon IL-13 activation of STAT6

Interleukin-25 or IL-17E is a member of IL-17 cytokine family and has immune-modulating activities. The role of IL-25 in maintaining lipid metabolic homeostasis remains unknown. We investigated the effects of exogenous IL-25 or deficiency of IL-25 on hepatic lipid accumulation. IL-25 expression was...

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Publicat a:J Immunol
Autors principals: Wang, An-Jiang, Yang, Zhonghan, Grinchuk, Viktoriya, Smith, Allen, Qin, Bolin, Lu, Nonghua, Wang, Duan, Wang, Hongbing, Ramalingam, Thirumalai R., Wynn, Thomas A., Urban, Joseph F., Shea-Donohue, Terez, Zhao, Aiping
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637252/
https://ncbi.nlm.nih.gov/pubmed/26423151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500337
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