Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice

BACKGROUND: IL-25 is emerging as a key regulator of inflammation in the intestinal mucosa because of its ability to promote type 2 while suppressing Th1 and Th17 responses. Several previous studies reported inconsistent results on the role of exogenous IL-25 in development of colonic inflammation an...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Wang, An-Jiang, Smith, Allen, Li, Yanfei, Urban, Joseph F, Ramalingam, Thirumalai R, Wynn, Thomas A, Lu, Nonghua, Shea-Donohue, Terez, Yang, Zhonghan, Zhao, Aiping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417544/
https://ncbi.nlm.nih.gov/pubmed/25937893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-4-72
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