Role of p14ARF-HDM2-p53 axis in SOX6-mediated tumor suppression

Sex-determining region Y box 6 (SOX6) has been described as a tumor-suppressor gene in several cancers. Our previous work has suggested that SOX6 upregulated p21(Waf1/Cip1)(p21) expression in a p53-dependent manner; however, the underlying mechanism has remained elusive. In this study, we confirmed...

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Vydáno v:Oncogene
Hlavní autoři: Wang, J, Ding, S, Duan, Z, Xie, Q, Zhang, T, Zhang, X, Wang, Y, Chen, X, Zhuang, H, Lu, F
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820682/
https://ncbi.nlm.nih.gov/pubmed/26119940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.234
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