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Nucleolar p14(ARF) Overexpression in Reed-Sternberg Cells in Hodgkin’s Lymphoma : Absence of p14(ARF)/Hdm2 Complexes Is Associated with Expression of Alternatively Spliced Hdm2 Transcripts
The development of human cancers is frequently associated with the silencing of the two major tumor suppressor pathways represented by retinoblastoma protein and p53. As the incidence of p53 mutations is significantly lower in Hodgkin’s lymphoma than in other neoplasias, we investigated whether the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850651/ https://ncbi.nlm.nih.gov/pubmed/11839577 |
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