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Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders

REELIN (RELN) is a large (420 kDa) glycoprotein that in adulthood is mostly synthesized in GABAergic neurons of corticolimbic structures. Upon secretion in the extracellular matrix (ECM), RELN binds to VLDL, APOE2, and α3β2 Integrin receptors located on dendritic shafts and spines of postsynaptic py...

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Bibliografski detalji
Izdano u:Front Cell Neurosci
Glavni autori: Guidotti, Alessandro, Grayson, Dennis R., Caruncho, Hector J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820443/
https://ncbi.nlm.nih.gov/pubmed/27092053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00089
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