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Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects

Both Reelin (RELN) and glutamate decarboxylase 67 (GAD1) have been implicated in the pathophysiology of Autism Spectrum Disorders (ASD). We have previously shown that both mRNAs are reduced in the cerebella (CB) of ASD subjects through a mechanism that involves increases in the amounts of MECP2 bind...

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Pubblicato in:Int J Dev Neurosci
Autori principali: Zhubi, A, Chen, Y, Guidotti, A, Grayson, DR
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575980/
https://ncbi.nlm.nih.gov/pubmed/28229923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijdevneu.2017.02.003
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