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Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders
REELIN (RELN) is a large (420 kDa) glycoprotein that in adulthood is mostly synthesized in GABAergic neurons of corticolimbic structures. Upon secretion in the extracellular matrix (ECM), RELN binds to VLDL, APOE2, and α3β2 Integrin receptors located on dendritic shafts and spines of postsynaptic py...
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| Publicat a: | Front Cell Neurosci |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820443/ https://ncbi.nlm.nih.gov/pubmed/27092053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00089 |
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