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An Inducible System for Rapid Degradation of Specific Cellular Proteins Using Proteasome Adaptors

A common way to study protein function is to deplete the protein of interest from cells and observe the response. Traditional methods involve disrupting gene expression but these techniques are only effective against newly synthesized proteins and leave previously existing and stable proteins untouc...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Wilmington, Shameika R., Matouschek, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820223/
https://ncbi.nlm.nih.gov/pubmed/27043013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152679
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