Safety and tolerability of AZD5363 in Japanese patients with advanced solid tumors

PURPOSE: Investigate the safety and tolerability of AZD5363 and define a recommended dose for evaluation in Japanese patients with advanced solid malignancies. METHODS: AZD5363 was administered orally as a single dose, and then the dose was escalated to twice daily (bid) in separate continuous (ever...

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Veröffentlicht in:Cancer Chemother Pharmacol
Hauptverfasser: Tamura, Kenji, Hashimoto, Jun, Tanabe, Yuko, Kodaira, Makoto, Yonemori, Kan, Seto, Takashi, Hirai, Fumihiko, Arita, Shuji, Toyokawa, Gouji, Chen, Lan, Yamamoto, Hiroshi, Kawata, Toshio, Lindemann, Justin, Esaki, Taito
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819940/
https://ncbi.nlm.nih.gov/pubmed/26931343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-2987-9
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