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Safety and tolerability of the olaparib tablet formulation in Japanese patients with advanced solid tumours
PURPOSE: This was the first Phase I study to assess the safety and tolerability of the tablet formulation of olaparib (Lynparza™), an oral poly(ADP-ribose) polymerase inhibitor, in Japanese patients with advanced solid tumours. The pharmacokinetic profile and antitumour activity of olaparib tablets...
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Udgivet i: | Cancer Chemother Pharmacol |
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Main Authors: | , , , , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Springer Berlin Heidelberg
2016
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010592/ https://ncbi.nlm.nih.gov/pubmed/27422301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3106-7 |
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