Identification of a Bipotent Epithelial Progenitor Population in the Adult Thymus

Thymic epithelial cells (TECs) are critically required for T cell development, but the cellular mechanisms that maintain adult TECs are poorly understood. Here, we show that a previously unidentified subpopulation, EpCam(+)UEA1(−)Ly-51(+)PLET1(+)MHC class II(hi), which comprises <0.5% of adult TE...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Ulyanchenko, Svetlana, O’Neill, Kathy E., Medley, Tanya, Farley, Alison M., Vaidya, Harsh J., Cook, Alistair M., Blair, Natalie F., Blackburn, C. Clare
Format: Artigo
Langue:Inglês
Publié: Cell Press 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819909/
https://ncbi.nlm.nih.gov/pubmed/26997270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.080
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