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Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions
Niemann‐pick type C1 (NPC1) is an endo/lysosomal membrane protein involved in intracellular cholesterol trafficking, and its luminal domain C is an essential endosomal receptor for Ebola and Marburg viruses. We have determined the crystal structure of glycosylated NPC1 luminal domain C and find all...
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| 發表在: | FEBS Lett |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819692/ https://ncbi.nlm.nih.gov/pubmed/26846330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12089 |
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