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Co-evolutionary Analysis of Domains in Interacting Proteins Reveals Insights into Domain–Domain Interactions Mediating Protein–Protein Interactions

Recent advances in functional genomics have helped generate large-scale high-throughput protein interaction data. Such networks, though extremely valuable towards molecular level understanding of cells, do not provide any direct information about the regions (domains) in the proteins that mediate th...

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Detalhes bibliográficos
Main Authors: Jothi, Raja, Cherukuri, Praveen F., Tasneem, Asba, Przytycka, Teresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618801/
https://ncbi.nlm.nih.gov/pubmed/16949097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.07.072
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