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Co-evolutionary Analysis of Domains in Interacting Proteins Reveals Insights into Domain–Domain Interactions Mediating Protein–Protein Interactions

Recent advances in functional genomics have helped generate large-scale high-throughput protein interaction data. Such networks, though extremely valuable towards molecular level understanding of cells, do not provide any direct information about the regions (domains) in the proteins that mediate th...

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Autori principali: Jothi, Raja, Cherukuri, Praveen F., Tasneem, Asba, Przytycka, Teresa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618801/
https://ncbi.nlm.nih.gov/pubmed/16949097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.07.072
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