Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

OBJECTIVE: An interesting and so far unexplained feature of chronic pain in autoimmune disease is the frequent disconnect between pain and inflammation. This is illustrated well in rheumatoid arthritis (RA) where pain in joints (arthralgia) may precede joint inflammation and persist even after succe...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Wigerblad, Gustaf, Bas, Duygu B, Fernades-Cerqueira, Cátia, Krishnamurthy, Akilan, Nandakumar, Kutty Selva, Rogoz, Katarzyna, Kato, Jungo, Sandor, Katalin, Su, Jie, Jimenez–Andrade, Juan Miguel, Finn, Anja, Bersellini Farinotti, Alex, Amara, Khaled, Lundberg, Karin, Holmdahl, Rikard, Jakobsson, Per-Johan, Malmström, Vivianne, Catrina, Anca I, Klareskog, Lars, Svensson, Camilla I
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819624/
https://ncbi.nlm.nih.gov/pubmed/26613766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-208094
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